June 8 (Monday), 2015
11:00 – 17:00 Arrival & Registration
18:15 – 18:30

Opening Keynote

INTRODUCTION of the Speaker by IGOR ŠTAGLJAR
18:30 – 19:20 Stan Fields(University of Washington, Seattle, USA)  “Deep mutational scanning to analyse protein function”
19:30 – 21:00 Songs, Mediterranean food and wine
 
   
June 9 (Tuesday), 2015
09:00 - 13:00 Morning session
 

OMICs and Aging/Neurodegenerative diseases (30’ talk+5minQs)

 SESSION CHAIR: Erich Wanker (MDC Berlin, Germany)
09:00 - 9:35 Adriano Aguzzi (University of Zurich, Switzerland)  “Molecular biology of prions”
09:35 - 10:10 Gaia Novarino (Institute for Science & Technology, Austria) “The HSPome: a journey in the genetic landscape of hereditary spastic paraplegias”
10:10 -10:30 Christoph H. Borchers (University of Victoria, Canada) “MRM-based assay kits for quantitative metabolomics in biomedical and clinical research”
10:30 - 11:00 Coffee break
11:00- 11:35 Paul Muchowski (KynuRex, USA) “Yeast As A Screening Tool For Protein Misfolding Diseases”
11:35 - 12:10

Wolfgang Baumeister (Max Plank, Martinsried, Germany)

 “The Challenge of doing Structural Biology in situ”
12:10 - 12:30 Maciej Lalowski (University of Helsinki, Finland) “Drafting the Neuronal Ceroid Lipofuscinosis 1 Interactome in the brain”
13:00 – 14:00 Lunch
14:00 – 15:00

1st WORKSHOP “Publishing high profile papers in OMICs research”

Moderator: Igor Štagljar

Natalie de Souza (Editor in Chief, Nature Methods)

Mirella Bucci (Senior Editor, Nature Chemical Biology)
15:00 – 17:00 Free activities
17:00 – 20:00 Evening session
 

OMICs and Networks (30’ talk + 5 min Qs)

SESSION CHAIR: Stan Fields (University of Washington, USA)
17:00 - 17:35 Charlie Boone (University of Toronto, Canada) “Modelling the Cell with Global Genetic Interaction Networks”
17:35 - 18:10 Anne-Claude Gavin (EMBL, Heidelberg, Germany)  “Protein-lipid networks”
18:10 - 18:45 Martin Beck (EMBL, Heidelberg, Germany) “Integrated genome and proteome-wide analysis reveals organ-specific proteome deterioration during aging in rat”
18:45 - 19:00

Berend Snijder (CeMM Research Centre, Vienna, Austria)

“Functional mapping of the lipid landscape in innate immunity”
19:00 - 19:15 Coffee break
19:15 - 19:50 Erich Wanker (MDC Berlin, Germany)  “Interactome maps for proteins involved in neurodegenerative diseases and synapse function”
19:50 - 20:25 Patrick Aloy (IRB, Barcelona, Spain) “A network biology approach to therapeutics”
20:30 - 21:30 Diner
 
   
June 10 (Wednesday), 2015
09:00 - 13:00 Morning session
  OMICs and Drug Discovery (30’ talk + 5 min Qs)
SESSION CHAIR: Paul Muchowski (KynuRex, USA)
9:00 - 9:35 Gerard Drewes (Cellzome/GSK, Heidelberg, Germany) “Tracking drugs in living cells by thermal profiling of the proteome”
09:35 - 10:10 Klaus Seuwen (Novartis, Basel, Switzerland) “Orphan G protein-coupled receptors in the human genome”
10:10 -10:45 Domagoj Vučić (Genentech, South San Francisco, USA) “Ubiquitination profiling reveals sensitivity factors in cancer and inflammatory diseases”
10:45 - 11:15 Coffee break
11:15 - 11:50 Slobodan Vukičević (University of Zagreb, Croatia) “Bone morphogenetic proteins in regenerative medicine”
11:50 - 12:25 Jörg Hoheisel (German Cancer Research Center, Heidelberg) “Affinity-based assays for personalised proteomics in cancer research”
12:25 - 12:40 Marija Tadin-Strapps (Merck,USA) “siRNA and CRISPR tools for target validation: Impact on early drug discovery”
12:40 – 13:00 Volker Kruft (AB SCIEX, Darmstadt, Germany) “Creating a digital image of any sample in the MS2 space: Discussing data-independent acquisition strategies”
13:00 - 14:00

Lunch

Small conference room

(13:00-14:00) Alphachrom Satellite Symposium
14:00 - 17:00

Free activities

Small conference room  

(16:00-17:00) SCIEX Workshop OneOmics and Swath
17:00 - 20:00 Evening session
 

OMICs & Cancer (30’ talk + 5 min Qs)

SESSION CHAIR: Ron Kopito (Stanford University, USA)
17:00 - 17:35 Siniša Volarević (University of Rijeka, Croatia) “Ribosome biogenesis stress and p53 regulation”
17:35 - 18:10 Igor Štagljar (University of Toronto, Canada) “Membrane Protein Interaction Networks in Cancer”
18:10 - 18:45 Kristijan Ramadan (University of Oxford, UK) ”Dynamic and reorganisation of p97/VCP -proteome after ionising radiation”
18:45 - 19:15 Coffee break
19:15 - 19:50 Thomas Kislinger (UHN, Toronto, Canada) “Systematic development of SRM-MS assays for the detection of aggressive prostate cancers”
19:50 - 20:05 Alexsander Buntru (Max Delbrueck Center, Berlin, Germany) “DULIP: a dual luminescence-based co-immunoprecipitation assay for interactome mapping in mammalian cells”
20:05 - 21:00 Dinner
21:00 - 23:00 Poster session
 
   
June 11 (Thursday), 2015
09:00 - 13:00 Morning session
 

Emerging “OMICs” technologies (30’ talk + 5 min Qs)

SESSION CHAIR:  Patrick Aloy  (IRB, Barcelona, Spain)
09:00 -  9:35 Brenda Andrews (University of Toronto, Canada) "Yeast proteome dynamics from single cell imaging and automated analysis”
09:35 - 10:10 Gavin Wright (Sanger Center, Hinxton, UK) “Using systematic extracellular protein interactions screens to identify and interactions that are essential for cellular recognition processes”
10:10 - 10:45 Hana Kovarova (Institute of Animal Physiology and Genetics, Czech Republic)“A Neural Progenitor differentiation Patterns of Surface and secreted proteins for Cell-Replacement therapies of Neuronal Disorders”
10:45 - 11:15 Coffee break
11:15 - 11:50 Uwe Sauer (ETH Zurich, Switzerland) “Metabolomics as a hypothesis generator”
11:50 - 12:25 Ola Söderberg (Uppsala University, Sweden) “Molecular tools for evaluation of cellular activity status”
12:25 - 12:45 Lovorka Grgurević (University of Zagreb, Croatia) “Utilizing osteogenic potential of BMP6 in developing new treatment options”
13:00 - 14:00 Lunch
14:00 - 20:00 Excursion
20:00 - 21:00 Dinner
 
   
June 12 (Friday), 2015
09:00 - 13:00 Morning session
 

OMICs & Microbes (30’ talk + 5 min Qs)

SESSION CHAIR: Uwe Sauer (ETH Zurich, Switzerland)
09:00 - 09:35 Henning Walczak (University College, London) “Linear Ubiquitin: at the crossroads of gene activation, cell death, inflammation and cancer”
09:35 - 10:10 Miroslav Radman (MedILS, Split, Croatia) “Are aging and age-related diseases phenotypes of protein damage?”
10:10 - 10:45 Michel Desjardins (University of Montreal)   “Understanding antigen presentation and the immune response in  the"OMICs"Era”
10:45 - 11:15 Coffee break
11:15 - 11:50 Eric Brown (McMaster University, Hamilton, Canada) “Small molecules as probes of complexity in microbial systems”
11:50 - 12:10 David Duffy (University College Dublin, Ireland) “MYCN Integrative Omics Enables Network-Based Therapeutic Target Discovery and Patient Stratification in Neuroblastoma”
12:10 - 12:30 Maria Pires Pacheco (University of Luxembourg, Luxembourg)  “Integrated metabolic modelling reveals cell-type specific control of the macrophage metabolic network”
12:30 - 12:50 Gordan Lauc  (University of Zagreb, Croatia) “Patient stratification beyond individual genes: Glycans as integrators of genes and environment”
12:50 - 13:10 Shaun Bilsborough (Agilent Technologies, UK ) “Addressing the challenges of integrating data in the multi-omics laboratory”
13:10 - 14:00 Lunch
14:00 - 16:00 Free activities
16:00 - 17:00

2nd WORKSHOP “Careers in OMICs-based disciplines”

Moderator: Mladen Merćep

Brenda Andrews  (University  of Toronto, Canada),

Marija Tadin-Strapps (Merck, USA)
17:00 -17:20 Jolanda van Leeuwen  (University of Toronto, Canada) “Mapping genetic suppression interactions on a global scale”
17:20- 17:30 Coffee break
17:30 - 17:45

Closing Keynote

INTRODUCTION of the Speaker by Miroslav Radman
17:45 – 18:20 Ron Kopito (Stanford University, USA) “Proteomic and functional genomic dissection of protein quality control  in the endoplasmic reticulum”
20:00 - 23:00 Conference Banquet
 
   
June 13 (Saturday), 2015
Departure
 

MedILS –Mediterranean Institute for Life Sciences

Meštrovićevo šetalište 45   HR 21000 Split      Republic of Croatia

tel: +385 (0)21 555 600   fax: +385 (0)21 555 605    e-mail: medils@medils.hr